Tiny-objective segmentation for spot signs on multi-phase CT angiography via contrastive learning with dynamic-updated positive-negative memory banks.

Journal: Computers in biology and medicine
Published Date: Jul 11, 2025

Abstract

BACKGROUND AND OBJECTIVE: Presence of spot sign on CT Angiography (CTA) is associated with hematoma growth in patients with intracerebral hemorrhage. Measuring spot sign volume over time may aid to predict hematoma expansion. Due to the difficulties that imaging characteristics of spot sign are similar with vein and calcification and spot signs are tiny appeared in CTA images to detect, our aim is to develop an automated method to pick up spot signs accurately.

Authors

  • Jianhai Zhang
    School of Computer Science and Technology, Dalian University of Technology, Dalian, China.
  • Mackenzie Horn
    Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Canada. Electronic address: mackenzie.horn1@ucalgary.ca.
  • Koji Tanaka
    Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Canada. Electronic address: koji.tanaka@ucalgary.ca.
  • Fouzi Bala
    Department of Clinical Neurosciences, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
  • Nishita Singh
    Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, 3330 Hospital Dr NW, Calgary, AB, Canada.
  • Faysal Benali
    Department of Clinical Neurosciences, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
  • Aravind Ganesh
    Department of Clinical Neurosciences, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
  • Andrew M Demchuk
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
  • Bijoy K Menon
    Calgary Stroke Program, University of Calgary, Calgary, Alberta, Canada.
  • Wu Qiu
    From the Calgary Stroke Program, Departments of Clinical Neurosciences (W.Q., H.K., E.T., J.M.O., M.G., M.D.H., A.M.D., B.K.M.), Radiology (M.G., M.D.H., A.M.D., B.K.M.), and Community Health Sciences (M.D.H., B.K.M.), University of Calgary, 239 Strathridge Pl SW, Calgary, AB, Canada T3H 4J2; Hotchkiss Brain Institute, Calgary, Alberta, Canada (M.G., M.D.H., A.M.D., B.K.M.), Department of Neurology, Keimyung University, Daegu, South Korea (S.I.S.); and Division of Neuroradiology, Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Basel, Switzerland (J.M.O.).

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