Ethicara for Responsible AI in Healthcare: A System for Bias Detection and AI Risk Management.

Journal: AMIA ... Annual Symposium proceedings. AMIA Symposium
PMID:

Abstract

The increasing torrents of health AI innovations hold promise for facilitating the delivery of patient-centered care. Yet the enablement and adoption of AI innovations in the healthcare and life science industries can be challenging with the rising concerns of AI risks and the potential harms to health equity. This paper describes Ethicara, a system that enables health AI risk assessment for responsible AI model development. Ethicara works by orchestrating a collection of self-analytics services that detect and mitigate bias and increase model transparency from harmonized data models. For the lack of risk controls currently in the health AI development and deployment process, the self-analytics tools enhanced by Ethicara are expected to provide repeatable and measurable controls to operationalize voluntary risk management frameworks and guidelines (e.g., NIST RMF, FDA GMLP) and regulatory requirements emerging from the upcoming AI regulations (e.g., EU AI Act, US Blueprint for an AI Bill of Rights). In addition, Ethicara provides plug-ins via which analytics results are incorporated into healthcare applications. This paper provides an overview of Ethicara's architecture, pipeline, and technical components and showcases the system's capability to facilitate responsible AI use, and exemplifies the types of AI risk controls it enables in the healthcare and life science industry.

Authors

  • Maria Kritharidou
    Pfizer Inc., New York, NY, USA.
  • Georgios Chrysogonidis
    Pfizer Inc., New York, NY, USA.
  • Tasos Ventouris
    Pfizer Inc., New York, NY, USA.
  • Vaios Tsarapastsanis
    Pfizer Inc., New York, NY, USA.
  • Danai Aristeridou
    Pfizer Inc., New York, NY, USA.
  • Anastasia Karatzia
    Pfizer Inc., New York, NY, USA.
  • Veena Calambur
    Drexel University, Philadelphia, PA, USA.
  • Ahsan Huda
    Pfizer Inc., New York, NY, USA.
  • Sabrina Hsueh
    Pfizer Inc., New York, NY, USA.