Chemical entity recognition in patents by combining dictionary-based and statistical approaches.

Journal: Database : the journal of biological databases and curation
Published Date:

Abstract

We describe the development of a chemical entity recognition system and its application in the CHEMDNER-patent track of BioCreative 2015. This community challenge includes a Chemical Entity Mention in Patents (CEMP) recognition task and a Chemical Passage Detection (CPD) classification task. We addressed both tasks by an ensemble system that combines a dictionary-based approach with a statistical one. For this purpose the performance of several lexical resources was assessed using Peregrine, our open-source indexing engine. We combined our dictionary-based results on the patent corpus with the results of tmChem, a chemical recognizer using a conditional random field classifier. To improve the performance of tmChem, we utilized three additional features, viz. part-of-speech tags, lemmas and word-vector clusters. When evaluated on the training data, our final system obtained an F-score of 85.21% for the CEMP task, and an accuracy of 91.53% for the CPD task. On the test set, the best system ranked sixth among 21 teams for CEMP with an F-score of 86.82%, and second among nine teams for CPD with an accuracy of 94.23%. The differences in performance between the best ensemble system and the statistical system separately were small.Database URL: http://biosemantics.org/chemdner-patents.

Authors

  • Saber A Akhondi
    Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Ewoud Pons
    Department of Medical Informatics, Erasmus University Medical Center, PO Box 2040, 3000 CA Rotterdam.
  • Zubair Afzal
    Department of Medical Informatics, Erasmus University Medical Center, PO Box 2040, 3000 CA Rotterdam.
  • Herman van Haagen
    Department of Medical Informatics, Erasmus University Medical Center, PO Box 2040, 3000 CA Rotterdam.
  • Benedikt F H Becker
    Department of Medical Informatics, Erasmus University Medical Center, PO Box 2040, 3000 CA Rotterdam.
  • Kristina M Hettne
    Department of Human Genetics, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.
  • Erik M van Mulligen
    Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Jan A Kors
    Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands j.kors@erasmusmc.nl.