Publication of nuclear magnetic resonance experimental data with semantic web technology and the application thereof to biomedical research of proteins.

Journal: Journal of biomedical semantics
Published Date:

Abstract

BACKGROUND: The nuclear magnetic resonance (NMR) spectroscopic data for biological macromolecules archived at the BioMagResBank (BMRB) provide a rich resource of biophysical information at atomic resolution. The NMR data archived in NMR-STAR ASCII format have been implemented in a relational database. However, it is still fairly difficult for users to retrieve data from the NMR-STAR files or the relational database in association with data from other biological databases.

Authors

  • Masashi Yokochi
    Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Naohiro Kobayashi
    Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Eldon L Ulrich
    Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
  • Akira R Kinjo
    Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Takeshi Iwata
    Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Yannis E Ioannidis
    Department of Informatics & Telecommunications, University of Athens, Athens, Greece.
  • Miron Livny
    Department of Computer Sciences, University of Wisconsin-Madison, Madison, WI, 53706, USA.
  • John L Markley
    Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
  • Haruki Nakamura
    Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Chojiro Kojima
    Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Toshimichi Fujiwara
    Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. tfjwr@protein.osaka-u.ac.jp.