Real-time multi-channel monitoring of burst-suppression using neural network technology during pediatric status epilepticus treatment.

Journal: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
PMID:

Abstract

OBJECTIVE: To develop a real-time monitoring system that has the potential to guide the titration of anesthetic agents in the treatment of pediatric status epilepticus (SE).

Authors

  • Christos Papadelis
    Jane and John Justin Institute for Mind Health, Cook Children's Health Care System, Fort Worth, TX 76104, USA.
  • Seyedeh Fatemeh Salimi Ashkezari
    Center for Fetal-Neonatal Neuroimaging and Developmental Science, Boston Children's Hospital, Harvard Medical School, 1 Autumn St, Boston, MA 02215, USA; Division of Newborn Medicine, Department of Medicine, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
  • Chiran Doshi
    Center for Fetal-Neonatal Neuroimaging and Developmental Science, Boston Children's Hospital, Harvard Medical School, 1 Autumn St, Boston, MA 02215, USA; Division of Newborn Medicine, Department of Medicine, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
  • Sigride Thome-Souza
    Department of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
  • Phillip L Pearl
    Department of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
  • P Ellen Grant
    Fetal-Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Robert C Tasker
    Department of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA; Department of Anesthesia, Perioperative and Pain Medicine, Division of Critical Care Medicine, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
  • Tobias Loddenkemper
    Department of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.