MetaPred2CS: a sequence-based meta-predictor for protein-protein interactions of prokaryotic two-component system proteins.

Journal: Bioinformatics (Oxford, England)
Published Date:

Abstract

MOTIVATION: Two-component systems (TCS) are the main signalling pathways of prokaryotes, and control a wide range of biological phenomena. Their functioning depends on interactions between TCS proteins, the specificity of which is poorly understood.

Authors

  • Altan Kara
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, SY23 3EB, UK. karaltn@gmail.com.
  • Martin Vickers
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, SY23 3EB, UK. mjv08@aber.ac.uk.
  • Martin Swain
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, SY23 3EB, UK. mts11@aber.ac.uk.
  • David E Whitworth
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, SY23 3EB, UK. dew@aber.ac.uk.
  • Narcis Fernandez-Fuentes
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, SY23 3EB, UK. narcis.fernandez@gmail.com.