Effect of Protein Repetitiveness on Protein-Protein Interaction Prediction Results Using Support Vector Machines.

Journal: Journal of computational biology : a journal of computational molecular cell biology
Published Date:

Abstract

BACKGROUND: There are many computational approaches to predict the protein-protein interactions using support vector machines (SVMs) with high performance. In fact, performance of currently reported methods are significantly over-estimated and affected by the object repetitiveness in the datasets used.

Authors

  • Jie Zhou
    Departments of Ultrasound, Jiading District Central Hospital Affiliated Shanghai University of Medicine &Health Sciences, Shanghai, China.