Extensive complementarity between gene function prediction methods.
Journal:
Bioinformatics (Oxford, England)
Published Date:
Aug 13, 2016
Abstract
MOTIVATION: The number of sequenced genomes rises steadily but we still lack the knowledge about the biological roles of many genes. Automated function prediction (AFP) is thus a necessity. We hypothesized that AFP approaches that draw on distinct genome features may be useful for predicting different types of gene functions, motivating a systematic analysis of the benefits gained by obtaining and integrating such predictions.