Higher order methylation features for clustering and prediction in epigenomic studies.

Journal: Bioinformatics (Oxford, England)

Published Date: Sep 1, 2016

Abstract

MOTIVATION: DNA methylation is an intensely studied epigenetic mark, yet its functional role is incompletely understood. Attempts to quantitatively associate average DNA methylation to gene expression yield poor correlations outside of the well-understood methylation-switch at CpG islands.

Authors

Chantriolnt-Andreas Kapourani

IANC, School of Informatics, University of Edinburgh, Edinburgh EH8 9AB, UK.
Guido Sanguinetti

IANC, School of Informatics, University of Edinburgh, Edinburgh EH8 9AB, UK Synthetic and Systems Biology, University of Edinburgh, Edinburgh EH9 3JD, UK.

Keywords

CpG Islands DNA Methylation Epigenomics Forecasting Gene Expression Genome Machine Learning Promoter Regions, Genetic

External Resources

View on PubMed Access via DOI PubMed (27587656)

Higher order methylation features for clustering and prediction in epigenomic studies.

Abstract

Authors

Keywords

External Resources

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