Diffuse intrinsic pontine gliomas in children: Interest of robotic frameless assisted biopsy. A technical note.

Journal: Neuro-Chirurgie
PMID:

Abstract

INTRODUCTION: Diffuse intrinsic pontine gliomas (DIPG) constitute 10-15% of all brain tumors in the pediatric population; currently prognosis remains poor, with an overall survival of 7-14 months. Recently the indication of DIPG biopsy has been enlarged due to the development of molecular biology and various ongoing clinical and therapeutic trials. Classically a biopsy is performed using a stereotactic frame assisted procedure but the workflow may sometimes be heavy and more complex especially in children. In this study the authors present their experience with frameless robotic-guided biopsy of DIPG in a pediatric population.

Authors

  • H A Coca
    Service de neurochirurgie CHU Hautepierre, 67098, Strasbourg cedex, France. Electronic address: andrescoca@hotmail.com.
  • H Cebula
    Service de neurochirurgie CHU Hautepierre, 67098, Strasbourg cedex, France.
  • M Benmekhbi
    Service de neurochirurgie CHU Hautepierre, 67098, Strasbourg cedex, France.
  • M P Chenard
    Service de pathologie CHU Hautepierre, 67098, Strasbourg cedex, France.
  • N Entz-Werle
    Service de pédiatrie, unité d'hématologie-oncologie CHU Hautepierre, 67098, Strasbourg cedex, France.
  • F Proust
    Service de neurochirurgie CHU Hautepierre, 67098, Strasbourg cedex, France.