Dynamically weighted evolutionary ordinal neural network for solving an imbalanced liver transplantation problem.

Journal: Artificial intelligence in medicine
PMID:

Abstract

OBJECTIVE: Create an efficient decision-support model to assist medical experts in the process of organ allocation in liver transplantation. The mathematical model proposed here uses different sources of information to predict the probability of organ survival at different thresholds for each donor-recipient pair considered. Currently, this decision is mainly based on the Model for End-stage Liver Disease, which depends only on the severity of the recipient and obviates donor-recipient compatibility. We therefore propose to use information concerning the donor, the recipient and the surgery, with the objective of allocating the organ correctly.

Authors

  • Manuel Dorado-Moreno
    Department of Computer Science and Numerical Analysis, University of Córdoba, Campus Universitario de Rabanales, "Albert Einstein Building", Third Floor, 14071 Córdoba, Spain. Electronic address: i92domom@uco.es.
  • María Pérez-Ortiz
    Department of Quantitative Methods, Universidad Loyola Andalucía, Escritor Castilla Aguayo 4, 14004 Córdoba, Spain.
  • Pedro A Gutiérrez
    Department of Computer Science and Numerical Analysis, University of Córdoba, Campus Universitario de Rabanales, "Albert Einstein Building", Third Floor, 14071 Córdoba, Spain.
  • Rubén Ciria
    Liver Transplantation Unit, Reina Sofía Hospital, Av. Menéndez Pidal, 14004 Córdoba, Spain.
  • Javier Briceño
    Liver Transplantation Unit, Reina Sofía Hospital, Av. Menéndez Pidal, 14004 Córdoba, Spain.
  • César Hervás-Martínez
    Department of Computer Science and Numerical Analysis, University of Córdoba, Campus Universitario de Rabanales, "Albert Einstein Building", Third Floor, 14071 Córdoba, Spain.