QAcon: single model quality assessment using protein structural and contact information with machine learning techniques.

Journal: Bioinformatics (Oxford, England)
Published Date:

Abstract

MOTIVATION: Protein model quality assessment (QA) plays a very important role in protein structure prediction. It can be divided into two groups of methods: single model and consensus QA method. The consensus QA methods may fail when there is a large portion of low quality models in the model pool.

Authors

  • Renzhi Cao
    Department of Computer Science, Pacific Lutheran University, Tacoma, WA, 98447, USA.
  • Badri Adhikari
    Department of Computer Science, University of Missouri, Columbia, MO 65211, USA.
  • Debswapna Bhattacharya
    Department of Electrical Engineering and Computer Science, Wichita State University, Wichita, KS, 67260, USA.
  • Miao Sun
    Department of Electrical and Computer Engineering.
  • Jie Hou
    Department of Computer Science, University of Missouri, Columbia, MO, 65211, USA.
  • Jianlin Cheng
    Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO, USA.