Novel Screening Tool for Stroke Using Artificial Neural Network.

Journal: Stroke
Published Date:

Abstract

BACKGROUND AND PURPOSE: The timely diagnosis of stroke at the initial examination is extremely important given the disease morbidity and narrow time window for intervention. The goal of this study was to develop a supervised learning method to recognize acute cerebral ischemia (ACI) and differentiate that from stroke mimics in an emergency setting.

Authors

  • Vida Abedi
    Department of Public Health Science, Penn State College of Medicine, Hershey, PA, USA.
  • Nitin Goyal
    Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Georgios Tsivgoulis
    Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital, Athens, Greece.
  • Niyousha Hosseinichimeh
    From the Biocomplexity Institute (V.A., R.Z.), Department of Industrial and Systems Engineering (G.T.), and Nutritional Immunology and Molecular Medicine Laboratory, Biocomplexity Institute (R.H., J.B.-R.), Virginia Tech, Blacksburg; Biomedical and Translational Informatics Institute (V.A.) and Department of Neurology (R.Z.), Geisinger Health System, Danville, PA; Department of Neurology, University of Tennessee Health Science Center, Memphis (N.G., G.T., L.E., J.E.M., A.W.A., A.V.A., R.Z.); Second Department of Neurology, "Attikon University Hospital," School of Medicine, University of Athens, Greece (N.H.); and Neurovascular Imaging Research Core and UCLA Stroke Center, University of California, Los Angeles (D.S.L.).
  • Raquel Hontecillas
    From the Biocomplexity Institute (V.A., R.Z.), Department of Industrial and Systems Engineering (G.T.), and Nutritional Immunology and Molecular Medicine Laboratory, Biocomplexity Institute (R.H., J.B.-R.), Virginia Tech, Blacksburg; Biomedical and Translational Informatics Institute (V.A.) and Department of Neurology (R.Z.), Geisinger Health System, Danville, PA; Department of Neurology, University of Tennessee Health Science Center, Memphis (N.G., G.T., L.E., J.E.M., A.W.A., A.V.A., R.Z.); Second Department of Neurology, "Attikon University Hospital," School of Medicine, University of Athens, Greece (N.H.); and Neurovascular Imaging Research Core and UCLA Stroke Center, University of California, Los Angeles (D.S.L.).
  • Josep Bassaganya-Riera
    From the Biocomplexity Institute (V.A., R.Z.), Department of Industrial and Systems Engineering (G.T.), and Nutritional Immunology and Molecular Medicine Laboratory, Biocomplexity Institute (R.H., J.B.-R.), Virginia Tech, Blacksburg; Biomedical and Translational Informatics Institute (V.A.) and Department of Neurology (R.Z.), Geisinger Health System, Danville, PA; Department of Neurology, University of Tennessee Health Science Center, Memphis (N.G., G.T., L.E., J.E.M., A.W.A., A.V.A., R.Z.); Second Department of Neurology, "Attikon University Hospital," School of Medicine, University of Athens, Greece (N.H.); and Neurovascular Imaging Research Core and UCLA Stroke Center, University of California, Los Angeles (D.S.L.).
  • Lucas Elijovich
    From the Biocomplexity Institute (V.A., R.Z.), Department of Industrial and Systems Engineering (G.T.), and Nutritional Immunology and Molecular Medicine Laboratory, Biocomplexity Institute (R.H., J.B.-R.), Virginia Tech, Blacksburg; Biomedical and Translational Informatics Institute (V.A.) and Department of Neurology (R.Z.), Geisinger Health System, Danville, PA; Department of Neurology, University of Tennessee Health Science Center, Memphis (N.G., G.T., L.E., J.E.M., A.W.A., A.V.A., R.Z.); Second Department of Neurology, "Attikon University Hospital," School of Medicine, University of Athens, Greece (N.H.); and Neurovascular Imaging Research Core and UCLA Stroke Center, University of California, Los Angeles (D.S.L.).
  • Jeffrey E Metter
    From the Biocomplexity Institute (V.A., R.Z.), Department of Industrial and Systems Engineering (G.T.), and Nutritional Immunology and Molecular Medicine Laboratory, Biocomplexity Institute (R.H., J.B.-R.), Virginia Tech, Blacksburg; Biomedical and Translational Informatics Institute (V.A.) and Department of Neurology (R.Z.), Geisinger Health System, Danville, PA; Department of Neurology, University of Tennessee Health Science Center, Memphis (N.G., G.T., L.E., J.E.M., A.W.A., A.V.A., R.Z.); Second Department of Neurology, "Attikon University Hospital," School of Medicine, University of Athens, Greece (N.H.); and Neurovascular Imaging Research Core and UCLA Stroke Center, University of California, Los Angeles (D.S.L.).
  • Anne W Alexandrov
    From the Biocomplexity Institute (V.A., R.Z.), Department of Industrial and Systems Engineering (G.T.), and Nutritional Immunology and Molecular Medicine Laboratory, Biocomplexity Institute (R.H., J.B.-R.), Virginia Tech, Blacksburg; Biomedical and Translational Informatics Institute (V.A.) and Department of Neurology (R.Z.), Geisinger Health System, Danville, PA; Department of Neurology, University of Tennessee Health Science Center, Memphis (N.G., G.T., L.E., J.E.M., A.W.A., A.V.A., R.Z.); Second Department of Neurology, "Attikon University Hospital," School of Medicine, University of Athens, Greece (N.H.); and Neurovascular Imaging Research Core and UCLA Stroke Center, University of California, Los Angeles (D.S.L.).
  • David S Liebeskind
    From the Biocomplexity Institute (V.A., R.Z.), Department of Industrial and Systems Engineering (G.T.), and Nutritional Immunology and Molecular Medicine Laboratory, Biocomplexity Institute (R.H., J.B.-R.), Virginia Tech, Blacksburg; Biomedical and Translational Informatics Institute (V.A.) and Department of Neurology (R.Z.), Geisinger Health System, Danville, PA; Department of Neurology, University of Tennessee Health Science Center, Memphis (N.G., G.T., L.E., J.E.M., A.W.A., A.V.A., R.Z.); Second Department of Neurology, "Attikon University Hospital," School of Medicine, University of Athens, Greece (N.H.); and Neurovascular Imaging Research Core and UCLA Stroke Center, University of California, Los Angeles (D.S.L.).
  • Andrei V Alexandrov
    From the Biocomplexity Institute (V.A., R.Z.), Department of Industrial and Systems Engineering (G.T.), and Nutritional Immunology and Molecular Medicine Laboratory, Biocomplexity Institute (R.H., J.B.-R.), Virginia Tech, Blacksburg; Biomedical and Translational Informatics Institute (V.A.) and Department of Neurology (R.Z.), Geisinger Health System, Danville, PA; Department of Neurology, University of Tennessee Health Science Center, Memphis (N.G., G.T., L.E., J.E.M., A.W.A., A.V.A., R.Z.); Second Department of Neurology, "Attikon University Hospital," School of Medicine, University of Athens, Greece (N.H.); and Neurovascular Imaging Research Core and UCLA Stroke Center, University of California, Los Angeles (D.S.L.).
  • Ramin Zand
    Neuroscience Institute, Geisinger Health System, 100 North Academy Ave, Danville, PA 17822, USA.