AIMC Topic: Brain Ischemia

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Association between lipid profiles and early clinical outcomes in acute ischemic stroke: a single-center cohort study in the Chinese population.

BMC neurology
BACKGROUND: The clinical significance and contribution of the lipid profile in atherosclerosis are well established. However, further investigation is needed in stroke patients, particularly regarding apolipoprotein B100 (ApoB100), a novel non-tradit...

Characterization of SPTLC2 as a key driver promoting microglial activation and energy metabolism reprogramming after ischemic stroke through bulk and single-cell analyses combined with experimental validation.

Cell biology and toxicology
BACKGROUND: Ischemic stroke (IS) stands as a principal contributor to high rates of sickness and death. The condition's pathological development is complicated, featuring mechanisms like mitochondrial impairment and the activation of microglial cells...

Development of a deep learning method to identify acute ischaemic stroke lesions on brain CT.

Stroke and vascular neurology
BACKGROUND: CT is commonly used to image patients with ischaemic stroke but radiologist interpretation may be delayed. Machine learning techniques can provide rapid automated CT assessment but are usually developed from annotated images which necessa...

Development of a non-contrast CT-based radiomics nomogram for early prediction of delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage.

BMC medical imaging
BACKGROUNDS: Delayed cerebral ischemia (DCI) is a significant complication following aneurysmal subarachnoid hemorrhage (aSAH), leading to poor prognosis and high mortality. This study developed a non-contrast CT (NCCT)-based radiomics nomogram for e...

Quantitative Ischemic Lesions of Portable Low-Field Strength MRI Using Deep Learning-Based Super-Resolution.

Stroke
BACKGROUND: Deep learning-based synthetic super-resolution magnetic resonance imaging (SynthMRI) may improve the quantitative lesion performance of portable low-field strength magnetic resonance imaging (LF-MRI). The aim of this study is to evaluate ...

Machine Learning for the Early Prediction of Delayed Cerebral Ischemia in Patients With Subarachnoid Hemorrhage: Systematic Review and Meta-Analysis.

Journal of medical Internet research
BACKGROUND: Delayed cerebral ischemia (DCI) is a primary contributor to death after subarachnoid hemorrhage (SAH), with significant incidence. Therefore, early determination of the risk of DCI is an urgent need. Machine learning (ML) has received muc...

Leveraging machine learning algorithms to forecast delayed cerebral ischemia following subarachnoid hemorrhage: a systematic review and meta-analysis of 5,115 participants.

Neurosurgical review
It is feasible to predict delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH) using Artificial intelligence (AI) algorithms, which may offer significant improvements in early diagnosis and patient management. This systemat...

Deep learning-based segmentation of acute ischemic stroke MRI lesions and recurrence prediction within 1 year after discharge: A multicenter study.

Neuroscience
OBJECTIVE: To explore the performance of deep learning-based segmentation of infarcted lesions in the brain magnetic resonance imaging (MRI) of patients with acute ischemic stroke (AIS) and the recurrence prediction value of radiomics within 1 year a...

Predictive etiological classification of acute ischemic stroke through interpretable machine learning algorithms: a multicenter, prospective cohort study.

BMC medical research methodology
BACKGROUND: The prognosis, recurrence rates, and secondary prevention strategies varied significantly among different subtypes of acute ischemic stroke (AIS). Machine learning (ML) techniques can uncover intricate, non-linear relationships within med...

Integrating Clinical Data and Radiomics and Deep Learning Features for End-to-End Delayed Cerebral Ischemia Prediction on Noncontrast CT.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Delayed cerebral ischemia is hard to diagnose early due to gradual, symptomless development. This study aimed to develop an automated model for predicting delayed cerebral ischemia following aneurysmal SAH on NCCT.