Synaptic damage underlies EEG abnormalities in postanoxic encephalopathy: A computational study.

Journal: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
PMID: 28753456

Abstract

OBJECTIVE: In postanoxic coma, EEG patterns indicate the severity of encephalopathy and typically evolve in time. We aim to improve the understanding of pathophysiological mechanisms underlying these EEG abnormalities.

Authors

  • B J Ruijter
    Clinical Neurophysiology, MIRA - Institute for Biomedical Technology and Technical Medicine, University of Twente, Hallenweg 15, 7522NB Enschede, The Netherlands. Electronic address: b.j.ruijter@utwente.nl.
  • J Hofmeijer
    Clinical Neurophysiology, MIRA - Institute for Biomedical Technology and Technical Medicine, University of Twente, Hallenweg 15, 7522NB Enschede, The Netherlands; Department of Neurology, Rijnstate Hospital, Wagnerlaan 55, 6815AD Arnhem, The Netherlands.
  • H G E Meijer
    Applied Mathematics, MIRA - Institute for Biomedical Technology and Technical Medicine, University of Twente, Hallenweg 15, 7522NB Enschede, The Netherlands.
  • M J A M van Putten
    Clinical Neurophysiology, MIRA - Institute for Biomedical Technology and Technical Medicine, University of Twente, Hallenweg 15, 7522NB Enschede, The Netherlands; Departments of Neurology and Clinical Neurophysiology, Medisch Spectrum Twente, Koningsplein 1, 7512KZ Enschede, The Netherlands.

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