BACKGROUND: Current clinical guidelines recommend gene expression profiling to guide treatment in early-stage breast cancer. PreciseBreast (PDxBR) is a digital prognostic tool that integrates artificial intelligence (AI)-derived features from hematox...
BACKGROUND: A substantial number of individuals in disability care experience challenges with daily structure and planning and require 24-7 support. The use of a social robot might decrease their need for support from care professionals, leading to i...
BMC medical informatics and decision making
Jul 21, 2025
BACKGROUND: Nosocomial infections are a major cause of morbidity and mortality in the ICU. Earlier identification of these complications may facilitate better clinical management and improve outcomes. We developed a dynamic prediction model that leve...
BACKGROUND AND PURPOSE: Treatment-related shared decision-making (SDM) in older adults with hip fractures is complex due to the need to balance patient-specific factors such as life goals, frailty, and surgical risks. It includes considerations such...
Effective management of energy and water resources is essential for mitigating environmental impacts and enhancing sustainability. This paper proposes a multiple-objective linear program tailored to accommodate energy-water applications in diverse cl...
The British journal of general practice : the journal of the Royal College of General Practitioners
May 2, 2025
BACKGROUND: The journey of >80% of patients diagnosed with lung cancer starts in general practice. About 75% of patients are diagnosed when it is at an advanced stage (3 or 4), leading to >80% mortality within 1 year at present. The long-term data in...
BACKGROUND: Exclusion of coronary stenosis in individuals with suggestive symptoms is challenging. Cardiac CT or coronary angiography is often used but is inefficient and costly and involves risks. Sex-stratified algorithms based on electronic health...
The spine journal : official journal of the North American Spine Society
Mar 26, 2025
BACKGROUND CONTEXT: When treating spinal metastases in a palliative setting, maintaining or enhancing quality of life (QoL) is the primary therapeutic objective. Clinicians tailor their treatment strategy by weighing the QoL benefits against expected...
BMC medical informatics and decision making
Mar 7, 2025
BACKGROUND: Clinical machine learning research and artificial intelligence driven clinical decision support models rely on clinically accurate labels. Manually extracting these labels with the help of clinical specialists is often time-consuming and ...
World journal of emergency surgery : WJES
Dec 23, 2024
BACKGROUND: Acute abdominal pain (AAP) constitutes 5-10% of all emergency department (ED) visits, with appendicitis being a prevalent AAP etiology often necessitating surgical intervention. The variability in AAP symptoms and causes, combined with th...
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