Utilizing knowledge base of amino acids structural neighborhoods to predict protein-protein interaction sites.
Journal:
BMC bioinformatics
Published Date:
Dec 6, 2017
Abstract
BACKGROUND: Protein-protein interactions (PPI) play a key role in an investigation of various biochemical processes, and their identification is thus of great importance. Although computational prediction of which amino acids take part in a PPI has been an active field of research for some time, the quality of in-silico methods is still far from perfect.