A Hybrid Residual Network and Long Short-Term Memory Method for Peptic Ulcer Bleeding Mortality Prediction.

Journal: AMIA ... Annual Symposium proceedings. AMIA Symposium
Published Date:

Abstract

The prediction of patient mortality, which can detect high-risk patients, is a significant yet challenging problem in medical informatics. Thanks to the wide adoption of electronic health records (EHRs), many data-driven methods have been proposed to forecast mortality. However, most existing methods do not consider correlations between static and dynamic data, which contain significant information about mutual influences between these data. In this paper, we utilize a deep Residual Network (ResNet) consisting of many convolution units, which can jointly analyze different variables, to capture correlation information in and between static and dynamic variables. Furthermore, the Long Short-Term Memory (LSTM) method is used to extract temporal dependencies information from dynamic data. Finally, a deep fusion method is used to integrate these different types of information to improve mortality prediction. Experiment results on Peptic Ulcer Bleeding (PUB) mortality prediction show that the proposed method outperforms existing methods and achieves an AUC (area under the receiver operating characteristic curve) score of 0.9353.

Authors

  • Qingxing Tan
    Hong Kong Baptist University, Hong Kong.
  • Andy Jinhua Ma
    Hong Kong Baptist University, Hong Kong.
  • Huiqi Deng
    Hong Kong Baptist University, Hong Kong.
  • Vincent Wai-Sun Wong
    Medical Data Analytics Center, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.
  • Yee-Kit Tse
    The Chinese University of Hong Kong, Hong Kong.
  • Terry Cheuk-Fung Yip
    Medical Data Analytics Center, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.
  • Grace Lai-Hung Wong
    Medical Data Analytics Center, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.
  • Jessica Yuet-Ling Ching
    The Chinese University of Hong Kong, Hong Kong.
  • Francis Ka-Leung Chan
    The Chinese University of Hong Kong, Hong Kong.
  • Pong-Chi Yuen
    Hong Kong Baptist University, Hong Kong.