A Network Integration Method for Deciphering the Types of Metabolic Pathway of Chemicals with Heterogeneous Information.
Journal:
Combinatorial chemistry & high throughput screening
Published Date:
Jan 1, 2018
Abstract
AIM AND OBJECTIVE: A metabolic pathway is an important type of biological pathway, which is composed of a series of chemical reactions. It provides essential molecules and energies for living organisms. To date, several metabolic pathways have been uncovered. However, their completeness is still on the way. A number of prediction methods have been built to assign chemicals into certain metabolic pathway, which can further be used to predict novel latent chemicals for a given metabolic pathway. However, they did not make use of chemical properties in a system level to construct prediction models.