Development of a deep convolutional neural network to predict grading of canine meningiomas from magnetic resonance images.

Journal: Veterinary journal (London, England : 1997)
Published Date:

Abstract

An established deep neural network (DNN) based on transfer learning and a newly designed DNN were tested to predict the grade of meningiomas from magnetic resonance (MR) images in dogs and to determine the accuracy of classification of using pre- and post-contrast T1-weighted (T1W), and T2-weighted (T2W) MR images. The images were randomly assigned to a training set, a validation set and a test set, comprising 60%, 10% and 30% of images, respectively. The combination of DNN and MR sequence displaying the highest discriminating accuracy was used to develop an image classifier to predict the grading of new cases. The algorithm based on transfer learning using the established DNN did not provide satisfactory results, whereas the newly designed DNN had high classification accuracy. On the basis of classification accuracy, an image classifier built on the newly designed DNN using post-contrast T1W images was developed. This image classifier correctly predicted the grading of 8 out of 10 images not included in the data set.

Authors

  • T Banzato
    Department of Animal Medicine, Production and Health, Clinical Section, Radiology Unit, University of Padua, Viale dell'Università 16, Legnaro 35020, Padua, Italy.
  • G B Cherubini
    Dick White Referrals (Cherubini), Six Mile Bottom, Cambridgeshire CB8 0UH, UK.
  • M Atzori
    Information Systems Institute, University of Applied Sciences Western Switzerland (HES-SO Valais), 3960 Sierre, Switzerland.
  • A Zotti
    Department of Animal Medicine, Production and Health, Clinical Section, Radiology Unit, University of Padua, Viale dell'Università 16, Legnaro 35020, Padua, Italy. Electronic address: alessadro.zotti@unipd.it.