Use of text-mining methods to improve efficiency in the calculation of drug exposure to support pharmacoepidemiology studies.

Journal: International journal of epidemiology
Published Date:

Abstract

BACKGROUND: Efficient generation of structured dose instructions that enable researchers to calculate drug exposure is central to pharmacoepidemiology studies. Our aim was to design and test an algorithm to codify dose instructions, applied to the NHS Scotland Prescribing Information System (PIS) that records about 100 million prescriptions per annum.

Authors

  • Stuart McTaggart
    Public Health and Intelligence Strategic Business Unit, NHS National Services Scotland, Edinburgh, UK.
  • Clifford Nangle
    Public Health and Intelligence Strategic Business Unit, NHS National Services Scotland, Edinburgh, UK.
  • Jacqueline Caldwell
    Public Health and Intelligence Strategic Business Unit, NHS National Services Scotland, Edinburgh, UK.
  • Samantha Alvarez-Madrazo
    Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
  • Helen Colhoun
    Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
  • Marion Bennie
    Public Health and Intelligence Strategic Business Unit, NHS National Services Scotland, Edinburgh, UK.