Role of irisin and myostatin on sarcopenia in malnourished patients diagnosed with GLIM criteria.

Journal: Nutrition (Burbank, Los Angeles County, Calif.)
PMID: 38309190

Abstract

OBJECTIVES: Sarcopenia is characterized by the loss of muscle mass. Skeletal muscle can produce and secrete different molecules called myokines. Irisin and myostatin are antagonistic myokines, and to our knowledge, no studies of both myokines have been conducted in patients with disease-related malnutrition (DRM). This study aimed to investigate the role of circulating irisin and myostatin in sarcopenia in patients with DRM.

Authors

  • Daniel de Luis
    Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School, Department of Endocrinology and Nutrition Hospital Clinico Universitario, University of Valladolid, Valladolid Spain. Electronic address: dadluis@yahoo.es.
  • David Primo
    Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School, Department of Endocrinology and Nutrition Hospital Clinico Universitario, University of Valladolid, Valladolid Spain.
  • Olatz Izaola
    Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School, Department of Endocrinology and Nutrition Hospital Clinico Universitario, University of Valladolid, Valladolid Spain.
  • Juan José López Gómez
    Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School, Department of Endocrinology and Nutrition Hospital Clinico Universitario, University of Valladolid, Valladolid Spain.

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