Application of Artificial Neural Network in miRNA Biomarker Selection and Precise Diagnosis of Colorectal Cancer.

Journal: Iranian biomedical journal
Published Date:

Abstract

BACKGROUND: The early diagnosis of colorectal cancer (CRC) is associated with improved survival rates, and development of novel non-invasive, sensitive, and specific diagnostic tests is highly demanded. The objective of this paper was to identify commonly circulating microRNA (miRNA) biomarkers for use in CRC diagnosis.

Authors

  • Saeid Afshar
    Research Center for Molecular Medicine, Hamadan University of Medical Science, Hamadan, Iran.
  • Sepideh Afshar
    Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
  • Emily Warden
    Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
  • Hamed Manochehri
    Research Center for Molecular Medicine, Hamadan University of Medical Science, Hamadan, Iran.
  • Massoud Saidijam
    Research Center for Molecular Medicine, Hamadan University of Medical Science, Hamadan, Iran.