Adrenal incidentalomas, cortisol secretion and cancer: is there a real crosstalk?

Journal: Frontiers in endocrinology
PMID: 38264281

Abstract

BACKGROUND: Cortisol has immunomodulatory effects that increase the risk and evolution of several diseases. Cancer is characterized by a proinflammatory state in which cells exert impaired function and proliferation. The relation between cortisol secretion and increased risk of malignant neoplasm, or their behavior, has not been fully elucidated.

Authors

  • Aura D Herrera-Martínez
    Endocrinology & Nutrition Department, Hospital Reina Sofia, Córdoba, Spain.
  • Ángel Rebollo Román
    Endocrinology & Nutrition Department, Hospital Reina Sofia, Córdoba, Spain.
  • Eider Pascual Corrales
    Endocrinology & Nutrition Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
  • Cindy Idrobo
    Endocrinology & Nutrition Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
  • Paola Parra Ramírez
    Endocrinology & Nutrition Department, Hospital La Paz, Madrid, Spain.
  • Patricia Martín Rojas
    Endocrinology & Nutrition Department, Hospital La Paz, Madrid, Spain.
  • Cristina Robles Lázaro
    Endocrinology & Nutrition Department, Hospital de Salamanca, Salamanca, Spain.
  • Marta Araujo-Castro
    Endocrinology & Nutrition Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.

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