AIMC Topic: Thyroid Neoplasms

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Identification of prognostic genes related to T cell proliferation in papillary thyroid cancer based on single-cell RNA sequencing and bulk RNA sequencing data.

Clinical and experimental medicine
Papillary thyroid carcinoma (PTC) is the main pathological subtype of thyroid cancer. Given the strong association between T cells and PTC, this study focused on the prognostic value and potential molecular mechanisms of T cell proliferation-related ...

Size-Specific Predictors for Malignancy Risk in Follicular Thyroid Neoplasms: Machine Learning Analysis.

JMIR cancer
BACKGROUND: Surgeons often face challenges in distinguishing between benign and malignant follicular thyroid neoplasms (FTNs), particularly small tumors, until diagnostic surgery is performed.

AI-enhanced patient-specific dosimetry in I-131 planar imaging with a single oblique view.

Scientific reports
This study aims to enhance the dosimetry accuracy in I planar imaging by utilizing a single oblique view and Monte Carlo (MC) validated dose point kernels (DPKs) alongside the integration of artificial intelligence (AI) for accurate dose prediction w...

Can mutation abundance assess the biological behavior of BRAF-positive papillary thyroid carcinoma?

Journal of translational medicine
BACKGROUND: BRAF mutation is the most common genetic change in papillary thyroid carcinoma (PTC). Nevertheless, the association between BRAF mutation status and abundance and the biological behavior of PTC is unclear. Thus, this study investigated wh...

The value of machine learning based on spectral CT quantitative parameters in the distinguishing benign from malignant thyroid micro-nodules.

BMC cancer
BACKGROUND AND AIMS: More cases of thyroid micro-nodules have been diagnosed annually in recent years because of advancements in diagnostic technologies and increased public health awareness. To explore the application value of various machine learni...

Development and validation of a machine learning model for central compartmental lymph node metastasis in solitary papillary thyroid microcarcinoma via ultrasound imaging features and clinical parameters.

BMC medical imaging
BACKGROUND: Papillary thyroid microcarcinoma (PTMC) is the most common malignant subtype of thyroid cancer. Preoperative assessment of the risk of central compartment lymph node metastasis (CCLNM) can provide scientific support for personalized treat...

Fabrication of serum-based SERS-tailored 3D structures for thyroid cancer diagnosis.

Scientific reports
Early detection of thyroid cancer improves patient survival rate from 51.9% to 99.9%. Fine needle aspiration cytology is the primary method for diagnosing thyroid cancer; however, this method is associated with limitations, including diagnostic uncer...

Ultrasound-based classification of follicular thyroid Cancer using deep convolutional neural networks with transfer learning.

Scientific reports
This study aimed to develop and validate convolutional neural network (CNN) models for distinguishing follicular thyroid carcinoma (FTC) from follicular thyroid adenoma (FTA). Additionally, this current study compared the performance of CNN models wi...

A Novel Three-Stage AI-Assisted Approach for Accurate Differential Diagnosis and Classification of NIFTP and Thyroid Neoplasms.

Endocrine pathology
The recent introduction of the term non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) marked a pivotal shift in the classification of encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) lacking ...

Preoperative Identification of Papillary Thyroid Carcinoma Subtypes and Lymph Node Metastasis via Deep Learning-Assisted Surface-Enhanced Raman Spectroscopy.

ACS nano
Accurate preoperative diagnosis of papillary thyroid carcinoma (PTC) histological subtypes and lymph node metastasis is essential for formulating personalized treatment strategies. However, their preoperative diagnosis is challenged by the limited re...