Journal of cancer research and clinical oncology
Dec 17, 2025
BACKGROUND: Thyroid cancer (TC) is one of the most prevalent endocrine malignancies, and its recurrence presents a major clinical challenge that can adversely affect patient prognosis and treatment outcomes. Despite the progress in diagnostic methods...
Current guidelines recommend total thyroidectomy for all T3b differentiated thyroid carcinoma (DTC) with gross strap muscle invasion, yet evidence supporting this universal approach remains limited and conflicting. We analyzed 6,920 T3b DTC patients ...
Timely and accurate diagnosis is crucial in addressing the global rise in thyroid cancer, ensuring effective treatment strategies and improved patient outcomes. We present an intelligent classification method that couples an Adaptive Convolutional Ne...
BACKGROUND: Hashimoto's thyroiditis (HT) is a common benign thyroid disease that often coexists with papillary thyroid carcinoma (PTC). Owing to the diffuse changes in the thyroid caused by HT, PTCs can be challenging to detect using conventional ima...
Data heterogeneity critically limits distributed artificial intelligence (AI) in medical imaging. We propose HeteroSync Learning (HSL), a privacy-preserving framework that addresses heterogeneity through: (1) Shared Anchor Task (SAT) for cross-node r...
The clinical necessity of lymph node dissection in papillary thyroid carcinoma (PTC) surgery remains contentious. This study compared four logistic regression (LR) models (with distinct feature selection strategies) and four machine learning (ML) mod...
Feature selection (FS) is critical for datasets with multiple variables and features, as it helps eliminate irrelevant elements, thereby improving classification accuracy. Numerous classification strategies are effective in selecting key features fro...
The histological identification of papillary thyroid carcinoma (PTC) is straightforward for experienced endocrine pathologists. The increase in radical thyroidectomies led to a raise in the rate of postoperative incidental subcentimeter PTC foci and ...
Hyperspectral imaging has shown significant applicability in the medical field, particularly for its ability to represent spectral information that can differentiate specific biomolecular characteristics in tissue samples. However, the complexity of ...
Papillary thyroid carcinoma (PTC) is the main pathological subtype of thyroid cancer. Given the strong association between T cells and PTC, this study focused on the prognostic value and potential molecular mechanisms of T cell proliferation-related ...
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