Identification of tissue-specific tumor biomarker using different optimization algorithms.
Journal:
Genes & genomics
Published Date:
Apr 1, 2019
Abstract
BACKGROUND: Identification of differentially expressed genes, i.e., genes whose transcript abundance level differs across different biological or physiological conditions, was indeed a challenging task. However, the inception of transcriptome sequencing (RNA-seq) technology revolutionized the simultaneous measurement of the transcript abundance levels for thousands of genes.