Recognition of Lung Adenocarcinoma-specific Gene Pairs Based on Genetic Algorithm and Establishment of a Deep Learning Prediction Model.

Journal: Combinatorial chemistry & high throughput screening
Published Date:

Abstract

AIM AND OBJECTIVE: Lung cancer is a disease with a dismal prognosis and is the major cause of cancer deaths in many countries. Nonetheless, rapid technological developments in genome science guarantees more effective prevention and treatment strategies.

Authors

  • Zhongwei Zhao
    Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing, China.
  • Xiaoxi Fan
    Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Lishui Hospital of Zhejiang University, Lishui 323000, China.
  • Lili Yang
    Hunan Province Key Laboratory of Typical Environmental Pollution and Health Hazards, School of Public Health, University of South China, Hengyang 421001, China.
  • Jingjing Song
    Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Lishui Hospital of Zhejiang University, Lishui 323000, China.
  • Shiji Fang
    Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Lishui Hospital of Zhejiang University, Lishui 323000, China.
  • Jianfei Tu
    Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Lishui Hospital of Zhejiang University, Lishui 323000, China.
  • Minjiang Chen
    Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Lishui Hospital of Zhejiang University, Lishui 323000, China.
  • Jie Li
    Guangdong-Hong Kong-Macao Greater Bay Area Artificial Intelligence Application Technology Research Institute, Shenzhen Polytechnic University, Shenzhen, China.
  • Liyun Zheng
    School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, China.
  • Fazong Wu
    Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Lishui Hospital of Zhejiang University, Lishui 323000, China.
  • Dengke Zhang
    Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Lishui Hospital of Zhejiang University, Lishui 323000, China.
  • Xihui Ying
    Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Lishui Hospital of Zhejiang University, Lishui 323000, China.
  • Jiansong Ji
    Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Lishui Hospital of Zhejiang University, Lishui 323000, China.