A classification framework for exploiting sparse multi-variate temporal features with application to adverse drug event detection in medical records.

Journal: BMC medical informatics and decision making
Published Date:

Abstract

BACKGROUND: Adverse drug events (ADEs) as well as other preventable adverse events in the hospital setting incur a yearly monetary cost of approximately $3.5 billion, in the United States alone. Therefore, it is of paramount importance to reduce the impact and prevalence of ADEs within the healthcare sector, not only since it will result in reducing human suffering, but also as a means to substantially reduce economical strains on the healthcare system. One approach to mitigate this problem is to employ predictive models. While existing methods have been focusing on the exploitation of static features, limited attention has been given to temporal features.

Authors

  • Francesco Bagattini
    Dipartimento di Ingegneria dell'Informazione, University of Florence, Florence, Italy.
  • Isak Karlsson
    Department of Computer and Systems Sciences, Stockholm University, Stockholm, Sweden. isak-kar@dsv.su.se.
  • Jonathan Rebane
    Department of Computer and Systems Sciences, Stockholm University, Stockholm, Sweden.
  • Panagiotis Papapetrou
    Department of Computer and Systems Sciences, Stockholm University, Sweden. Electronic address: panagiotis@dsv.su.se.