A cascaded dual-pathway residual network for lung nodule segmentation in CT images.

Journal: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Published Date:

Abstract

It is difficult to obtain an accurate segmentation due to the variety of lung nodules in computed tomography (CT) images. In this study, we propose a data-driven model, called the Cascaded Dual-Pathway Residual Network (CDP-ResNet) to improve the segmentation of lung nodules in the CT images. Our approach incorporates the multi-view and multi-scale features of different nodules from CT images. The proposed residual block based dual-path network extracts local features and rich contextual information of lung nodules. In addition, we designed an improved weighted sampling strategy to select training samples based on the edge. The proposed method was extensively evaluated on an LIDC dataset, which contains 986 nodules. Experimental results show that the CDP-ResNet achieves superior segmentation performance with an average DICE score (standard deviation) of 81.58% (11.05) on the LIDC dataset. Moreover, we compared our results with those of four radiologists on the same dataset. The comparison shows that the CDP-ResNet is slightly better than human experts in terms of segmentation accuracy. Meanwhile, the proposed segmentation method outperforms existing methods.

Authors

  • Hong Liu
    Key Laboratory of Grain and Oil Processing and Food Safety of Sichuan Province, College of Food and Bioengineering, Xihua University Chengdu 610039 China xingyage1@163.com.
  • Haichao Cao
    School of Computer Science & Technology, Huazhong University of Science and Technology, Wuhan Shi, China.
  • Enmin Song
    School of Computer Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, 430074, China.
  • Guangzhi Ma
    Huazhong University of Science and Technology, School of Computer Science & Technology, Wuhan 430074, China.
  • Xiangyang Xu
    Huazhong University of Science and Technology, School of Computer Science & Technology, Wuhan 430074, China.
  • Renchao Jin
    School of Computer Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, 430074, China.
  • Yong Jin
    Department of Pharmaceutics, College of Pharmacy, Yanbian University, Yanji 133000, China.
  • Chih-Cheng Hung
    Center for Machine Vision and Security Research, Kennesaw State University, Marietta, GA, 30144, USA.