Convolutional Neural Networks to Detect Pediatric Apnea-Hypopnea Events from Oximetry.

Journal: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Published Date:

Abstract

Pediatric sleep apnea-hypopnea syndrome (SAHS) is a highly prevalent breathing disorder that is related to many negative consequences for the children's health and quality of life when it remains untreated. The gold standard for pediatric SAHS diagnosis (overnight polysomnography) has several limitations, which has led to the search for alternative tests. In this sense, automated analysis of overnight oximetry has emerged as a simplified technique. Previous studies have focused on the extraction of ad-hoc features from the blood oxygen saturation (SpO) signal, which may miss useful information related to apnea and hypopnea (AH) events. In order to overcome this limitation of traditional approaches, we propose the use of convolutional neural networks (CNN), a deep learning technique, to automatically detect AH events from the SpO raw data. CHAT-baseline dataset, composed of 453 SpO recordings, was used for this purpose. A CNN model was trained using 60-s segments from the SpO signal using a training set (50% of subjects). Optimum hyperparameters of the CNN architecture were obtained using a validation set (25% of subjects). This model was applied to a third test set (25% of subjects), reaching 93.6% accuracy to detect AH events. These results suggest that the application of CNN may be useful to detect changes produced in the oximetry signal by AH events in pediatric SAHS patients.

Authors

  • Fernando Vaquerizo-Villar
  • Daniel Alvarez
  • Leila Kheirandish-Gozal
    Department of Neurology, The University of Missouri School of Medicine, Columbia, MO, United States.
  • Gonzalo C GutiĆ©rrez-Tobal
    Biomedical Engineering Group, University of Valladolid, Valladolid, Spain.
  • Veronica Barroso-Garcia
  • Felix Del Campo
  • David Gozal
    Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, United States.
  • Roberto Hornero
    Biomedical Engineering Group, University of Valladolid, Valladolid, Spain.