UPLC-MS/MS Method for Detection of Etomidate and Its Metabolite Etomidate Acid Quantity in Blood.

Journal: Fa yi xue za zhi
PMID:

Abstract

OBJECTIVES: To establish a method for the simultaneous quantitative analysis of etomidate and its metabolite etomidate acid in blood, and to discuss its application value in actual cases.

Authors

  • Xing Han
    Anti-Drug Technology Center of Guangdong Province, National Anti-Drug Laboratory Guangdong Regional Center, Guangzhou 510230, China.
  • Xin Liu
    Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences, Weifang, Shandong, China.
  • Ming-Luo DU
    Anti-Drug Technology Center of Guangdong Province, National Anti-Drug Laboratory Guangdong Regional Center, Guangzhou 510230, China.
  • Ruo-Lun Xu
    Anti-Drug Technology Center of Guangdong Province, National Anti-Drug Laboratory Guangdong Regional Center, Guangzhou 510230, China.
  • Jia-Rong Li
    Anti-Drug Technology Center of Guangdong Province, National Anti-Drug Laboratory Guangdong Regional Center, Guangzhou 510230, China.
  • Chao Liu
    Anti-Drug Technology Center of Guangdong Province, National Anti-Drug Laboratory Guangdong Regional Center, Guangzhou 510230, China.
  • Wei-Guo Liu
    Anti-Drug Technology Center of Guangdong Province, National Anti-Drug Laboratory Guangdong Regional Center, Guangzhou 510230, China.