Novel deep learning model for more accurate prediction of drug-drug interaction effects.

Journal: BMC bioinformatics
Published Date:

Abstract

BACKGROUND: Predicting the effect of drug-drug interactions (DDIs) precisely is important for safer and more effective drug co-prescription. Many computational approaches to predict the effect of DDIs have been proposed, with the aim of reducing the effort of identifying these interactions in vivo or in vitro, but room remains for improvement in prediction performance.

Authors

  • Geonhee Lee
    Department of Computer Science and Engineering, Incheon National University, Incheon, 22012, South Korea.
  • Chihyun Park
    Dept. of Computer Science, Yonsei University, Seodaemun-gu, Seoul, Korea.
  • Jaegyoon Ahn
    Department of Integrative Biology and Physiology, University of California, Los Angeles, USA. Electronic address: jgahn@ucla.edu.