NDDRF: A risk factor knowledgebase for personalized prevention of neurodegenerative diseases.

Journal: Journal of advanced research
Published Date: Jun 20, 2021

Abstract

INTRODUCTION: Neurodegenerative diseases (NDDs) are a series of chronic diseases, which are associated with progressive loss of neuronal structure or function. The complex etiologies of the NDDs remain unclear, thus the prevention and early diagnosis of NDDs are critical to reducing the mortality and morbidity of these diseases.

Authors

  • Cheng Bi
    Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610212, Sichuan, China; Center for Systems Biology, Soochow University, Suzhou 215006, Jiangsu, China.
  • Shengrong Zhou
    Center for Systems Biology, Soochow University, Suzhou 215006, Jiangsu, China.
  • Xingyun Liu
    Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610212, Sichuan, China; Center for Systems Biology, Soochow University, Suzhou 215006, Jiangsu, China.
  • Yu Zhu
    Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610212, Sichuan, China; Department of Bioinformatics, School of Biology and Basic Medical Sciences, Soochow University, Suzhou 215123, Jiangsu, China.
  • Jia Yu
    Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610212, Sichuan, China; School of Clinical Medicine, Soochow University, Suzhou 215123, Jiangsu, China.
  • Xueli Zhang
    Center for Systems Biology, Soochow University, Suzhou 215006, Jiangsu, China.
  • Manhong Shi
    Center for Systems Biology, Soochow University, Suzhou 215006, Jiangsu, China.
  • Rongrong Wu
    Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610212, Sichuan, China; Center for Systems Biology, Soochow University, Suzhou 215006, Jiangsu, China.
  • Hongxin He
    Center for Systems Biology, Soochow University, Suzhou 215006, Jiangsu, China.
  • Chaoying Zhan
    Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610212, Sichuan, China; Center for Systems Biology, Soochow University, Suzhou 215006, Jiangsu, China.
  • Yuxin Lin
    School of Computer and Communication Engineering, University of Science and Technology Beijing, Beijing, China.
  • Bairong Shen
    Institute of Systems Genetics, Department of Critical Care Medicine, Frontiers Science Center for Disease-related Molecular Network, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610000, China.

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