Integrated robotics platform with haptic control differentiates subjects with Parkinson's disease from controls and quantifies the motor effects of levodopa.

Journal: Journal of neuroengineering and rehabilitation
PMID: 31655612

Abstract

BACKGROUND: The use of integrated robotic technology to quantify the spectrum of motor symptoms of Parkinson's Disease (PD) has the potential to facilitate objective assessment that is independent of clinical ratings. The purpose of this study is to use the KINARM exoskeleton robot to (1) differentiate subjects with PD from controls and (2) quantify the motor effects of dopamine replacement therapies (DRTs).

Authors

  • Pauline Gaprielian
    Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, K7L 3N6, Canada.
  • Stephen H Scott
    Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada. steve.scott@queensu.ca.
  • Catherine Lowrey
    Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, K7L 3N6, Canada.
  • Stuart Reid
    Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, K7L 3N6, Canada.
  • Giovanna Pari
    Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, K7L 3N6, Canada.
  • Ron Levy
    Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, K7L 3N6, Canada. ron.levy@queensu.ca.

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