Deep learning-based MR-to-CT synthesis: The influence of varying gradient echo-based MR images as input channels.

Journal: Magnetic resonance in medicine
Published Date:

Abstract

PURPOSE: To study the influence of gradient echo-based contrasts as input channels to a 3D patch-based neural network trained for synthetic CT (sCT) generation in canine and human populations.

Authors

  • Mateusz C Florkow
    Centre for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Frank Zijlstra
    Centre for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Koen Willemsen
    Department of Orthopedics, University Medical Center Utrecht, Utrecht, Netherlands.
  • Matteo Maspero
    Department of Radiation Oncology, Imaging and Cancer Division, University Medical Center Utrecht, Utrecht, The Netherlands; Computational Imaging Group for MR Diagnostics & Therapy, Center for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Cornelis A T van den Berg
    Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Linda G W Kerkmeijer
    Department of Radiotherapy, Division of Imaging & Oncology, University Medical Center Utrecht, Utrecht, Netherlands.
  • RenĂ© M Castelein
    Department of Orthopedics, University Medical Center Utrecht, Utrecht, Netherlands.
  • Harrie Weinans
    Department of Biomechanical Engineering, Faculty of Mechanical, Maritime, and Materials Engineering, Delft University of Technology (TU Delft), Mekelweg 2, 2628CD Delft, The Netherlands; Department of Orthopedics, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands; Department of Rheumatology, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands.
  • Max A Viergever
  • Marijn van Stralen
    Centre for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Peter R Seevinck
    Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands.