[Material properties and tensile strength prediction model of traditional Chinese medicine tablets based on PCA-RBF neural network].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Published Date:

Abstract

This paper constructs a prediction model of material attribute-tensile strength based on principal component analysis-radial basis neural network( PCA-RBF),in order to predict the formability of traditional Chinese medicine tablets. Firstly,design Expert8. 0 software was used to design the dosage of different types of extracts,the mixture of traditional Chinese medicine with different physical properties was obtained,the powder properties of each extract and the tensile strength of tablets were determined,the correlation of the original input layer data was eliminated by PCA,the new variables unrelated to each other were trained as the input data of RBF neural network,and the tensile strength of the tablets was predicted. The experimental results showed that the PCA-RBF model had a good predictive effect on the tensile strength of the tablet,the minimum relative error was 0. 25%,the maximum relative error was2. 21%,and the average error was 1. 35%,which had a high fitting degree and better network prediction accuracy. This study initially constructed a prediction model of material properties-tensile strength of Chinese herbal tablets based on PCA-RBF,which provided a reference for the establishment of effective quality control methods for traditional Chinese medicine preparations.

Authors

  • Hai-Ning Zhao
    Tianjin University of Traditional Chinese Medicine Tianjin 301617,China Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique,Ministry of Education,Tianjin University of Traditional Chinese Medicine Tianjin 301617,China.
  • Ya-Jing Wang
    Tianjin University of Traditional Chinese Medicine Tianjin 301617,China Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique,Ministry of Education,Tianjin University of Traditional Chinese Medicine Tianjin 301617,China.
  • Li-Na Shang
    Tianjin University of Traditional Chinese Medicine Tianjin 301617,China Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique,Ministry of Education,Tianjin University of Traditional Chinese Medicine Tianjin 301617,China.
  • Meng-Nan Zhou
    Tianjin University of Traditional Chinese Medicine Tianjin 301617,China Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique,Ministry of Education,Tianjin University of Traditional Chinese Medicine Tianjin 301617,China.
  • Yi Zhang
    Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Jilin University, Changchun, China.
  • Xiang-Yin Ye
    Tianjin University of Traditional Chinese Medicine Tianjin 301617,China Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique,Ministry of Education,Tianjin University of Traditional Chinese Medicine Tianjin 301617,China.
  • Yan-Wen Wang
    Tianjin University of Traditional Chinese Medicine Tianjin 301617,China Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique,Ministry of Education,Tianjin University of Traditional Chinese Medicine Tianjin 301617,China.
  • Di Gao
    Tianjin University of Traditional Chinese Medicine Tianjin 301617,China Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique,Ministry of Education,Tianjin University of Traditional Chinese Medicine Tianjin 301617,China.