Synthesizing images from multiple kernels using a deep convolutional neural network.

Journal: Medical physics
Published Date:

Abstract

PURPOSE: Filtering measured projections with a particular convolutional kernel is an essential step in analytic reconstruction of computed tomography (CT) images. A tradeoff between noise and spatial resolution exists for different choices of reconstruction kernel. In a clinical setting, this often requires producing multiple images reconstructed with different kernels for a single CT exam, which increases the burden of computation, networking, archival, and reading. We address this problem by training a deep convolutional neural network (CNN) to synthesize multiple input images into a single output image which exhibits low noise while also preserving features in images reconstructed with the sharpest kernels.

Authors

  • Andrew D Missert
    CT Clinical Innovation Center, Department of Radiology, Mayo Clinic, Rochester, MN, 55905, USA.
  • Lifeng Yu
    Hithink RoyalFlush Information Network Co., Ltd., Hangzhou 310023, China. yulifeng@myhexin.com.
  • Shuai Leng
    Department of Radiology, Mayo Clinic, Rochester, MN, 55905, USA.
  • Joel G Fletcher
    Department of Radiology, Mayo Clinic, Rochester, MN, 55905, USA.
  • Cynthia H McCollough
    Department of Radiology, Mayo Clinic, Rochester, MN, 55905, USA.