Determination of causes of death via spectrochemical analysis of forensic autopsies-based pulmonary edema fluid samples with deep learning algorithm.

Journal: Journal of biophotonics
Published Date:

Abstract

This study investigated whether infrared spectroscopy combined with a deep learning algorithm could be a useful tool for determining causes of death by analyzing pulmonary edema fluid from forensic autopsies. A newly designed convolutional neural network-based deep learning framework, named DeepIR and eight popular machine learning algorithms, were used to construct classifiers. The prediction performances of these classifiers demonstrated that DeepIR outperformed the machine learning algorithms in establishing classifiers to determine the causes of death. Moreover, DeepIR was generally less dependent on preprocessing procedures than were the machine learning algorithms; it provided the validation accuracy with a narrow range from 0.9661 to 0.9856 and the test accuracy ranging from 0.8774 to 0.9167 on the raw pulmonary edema fluid spectral dataset and the nine preprocessing protocol-based datasets in our study. In conclusion, this study demonstrates that the deep learning-equipped Fourier transform infrared spectroscopy technique has the potential to be an effective aid for determining causes of death.

Authors

  • Hancheng Lin
    Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai, China.
  • Yiwen Luo
    Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai, China.
  • Qiran Sun
    Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai, China.
  • Kaifei Deng
    Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Science, Ministry of Justice, Shanghai, 200063, China.
  • Yijiu Chen
    Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Science, Ministry of Justice, Shanghai, 200063, China. Electronic address: cyj1347@163.com.
  • Zhenyuan Wang
    Department of Forensic Pathology, College of Forensic Medicine, Xian Jiaotong University, Xi'an, Shaanxi, 710061, China.
  • Ping Huang
    Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.