AIMC Topic: Autopsy

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Operationalizing postmortem pathology-MRI association studies in Alzheimer's disease and related disorders with MRI-guided histology sampling.

Acta neuropathologica communications
Postmortem neuropathological examination, while the gold standard for diagnosing neurodegenerative diseases, often relies on limited regional sampling that may miss critical areas affected by Alzheimer's disease and related disorders. Ultra-high reso...

Post-Mortem imaging biobanks: Building data for reproducibility, standardization, and AI integration.

European journal of radiology
In recent years, post-mortem imaging has advanced with techniques such as Post-Mortem Computed Tomography (PMCT) and Post-Mortem Magnetic Resonance imaging (PMMR). PMCT is particularly useful for assessing skeletal injuries, vascular lesions, and est...

Convolutional Neural Networks for the segmentation of hippocampal structures in postmortem MRI scans.

Journal of neuroscience methods
BACKGROUND: The hippocampus plays a crucial role in memory and is one of the first structures affected by Alzheimer's disease. Postmortem MRI offers a way to quantify the alterations by measuring the atrophy of the inner structures of the hippocampus...

Sex estimation using skull silhouette images from postmortem computed tomography by deep learning.

Scientific reports
Prompt personal identification is required during disasters that can result in many casualties. To rapidly estimate sex based on skull structure, this study applied deep learning using two-dimensional silhouette images, obtained from head postmortem ...

Text mining of verbal autopsy narratives to extract mortality causes and most prevalent diseases using natural language processing.

PloS one
Verbal autopsy (VA) narratives play a crucial role in understanding and documenting the causes of mortality, especially in regions lacking robust medical infrastructure. In this study, we propose a comprehensive approach to extract mortality causes a...

Causes of death in individuals with lifetime major depression: a comprehensive machine learning analysis from a community-based autopsy center.

BMC psychiatry
BACKGROUND: Depression can be associated with increased mortality and morbidity, but no studies have investigated the specific causes of death based on autopsy reports. Autopsy studies can yield valuable and detailed information on pathological ailme...

Inconsistency between Human Observation and Deep Learning Models: Assessing Validity of Postmortem Computed Tomography Diagnosis of Drowning.

Journal of imaging informatics in medicine
Drowning diagnosis is a complicated process in the autopsy, even with the assistance of autopsy imaging and the on-site information from where the body was found. Previous studies have developed well-performed deep learning (DL) models for drowning d...

Automated detection of fatal cerebral haemorrhage in postmortem CT data.

International journal of legal medicine
During the last years, the detection of different causes of death based on postmortem imaging findings became more and more relevant. Especially postmortem computed tomography (PMCT) as a non-invasive, relatively cheap, and fast technique is progress...

A new, deep learning-based method for the analysis of autopsy kidney samples used to study sex differences in glomerular density and size in a forensic population.

International journal of legal medicine
Artificial intelligence (AI) is increasingly used in forensic anthropology and genetics to identify the victim and the cause of death. The large autopsy samples from persons with traumatic causes of death but without comorbidities also offer possibil...

Classification of rib fracture types from postmortem computed tomography images using deep learning.

Forensic science, medicine, and pathology
Human or time resources can sometimes fall short in medical image diagnostics, and analyzing images in full detail can be a challenging task. With recent advances in artificial intelligence, an increasing number of systems have been developed to assi...