Improving long QT syndrome diagnosis by a polynomial-based T-wave morphology characterization.

Journal: Heart rhythm
Published Date:

Abstract

BACKGROUND: Diagnosing long QT syndrome (LQTS) remains challenging because of a considerable overlap in QT interval between patients with LQTS and healthy subjects. Characterizing T-wave morphology might improve LQTS diagnosis.

Authors

  • Ben J M Hermans
    Department of Biomedical Engineering, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands.
  • Frank C Bennis
    Department of Biomedical Engineering, Maastricht University, PO Box 616, 6200 MD, Maastricht, Netherlands. MHeNS School for Mental Health and Neuroscience, Maastricht University, PO Box 616, 6200 MD, Maastricht, Netherlands.
  • Arja S Vink
    Heart Centre, Department of Clinical and Experimental Cardiology, Academic Medical Center, DD Amsterdam, the Netherlands.
  • Tijmen Koopsen
    Department of Biomedical Engineering, Maastricht University, Maastricht, The Netherlands; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
  • Aurore Lyon
    Department of Computer Science, British Heart Foundation, Oxford, UK aurore.lyon@cs.ox.ac.uk.
  • Arthur A M Wilde
    European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart (P.D.L., A.A.M.W.).
  • Dieter Nuyens
    Department of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium.
  • Tomas Robyns
    Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.
  • Laurent Pison
    Department of Cardiology, Maastricht University Medical Centre, AZ Maastricht, The Netherlands.
  • Pieter G Postema
    Heart Centre, Department of Clinical and Experimental Cardiology, Academic Medical Center, DD Amsterdam, the Netherlands.
  • Tammo Delhaas