Distributed learning on 20 000+ lung cancer patients - The Personal Health Train.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Published Date: Jan 3, 2020

Abstract

BACKGROUND AND PURPOSE: Access to healthcare data is indispensable for scientific progress and innovation. Sharing healthcare data is time-consuming and notoriously difficult due to privacy and regulatory concerns. The Personal Health Train (PHT) provides a privacy-by-design infrastructure connecting FAIR (Findable, Accessible, Interoperable, Reusable) data sources and allows distributed data analysis and machine learning. Patient data never leaves a healthcare institute.

Authors

  • Timo M Deist
    Department of Radiation Oncology (MAASTRO Clinic), Dr. Tanslaan 12, Maastricht, The Netherlands.
  • Frank J W M Dankers
    Department of Radiation Oncology, GROW, School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Priyanka Ojha
    Department of Radiation Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
  • M Scott Marshall
    Department of Radiation Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
  • Tomas Janssen
    Department of Radiation Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
  • Corinne Faivre-Finn
    c The University of Manchester, Manchester Academic Health Science Centre, The Christie NHS Foundation Trust , Manchester , UK.
  • Carlotta Masciocchi
    Istituto di Radiologia, Universitá Cattolica del Sacro Cuore, Largo F.Vito 1, 00168 Rome, Italy.
  • Vincenzo Valentini
    Agostino Gemelli University Polyclinic (IRCCS), Rome, Italy.
  • Jiazhou Wang
    Department of radiation oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
  • Jiayan Chen
    Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
  • Zhen Zhang
    School of Pharmacy, Jining Medical University, Rizhao, Shandong, China.
  • Emiliano Spezi
  • Mick Button
    Velindre Cancer Centre, Cardiff, United Kingdom.
  • Joost Jan Nuyttens
    Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • René Vernhout
    Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Johan van Soest
    Department of Radiation Oncology (MAASTRO Clinic), Dr. Tanslaan 12, Maastricht, The Netherlands.
  • Arthur Jochems
    a Department of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology , Maastricht University Medical Centre , Maastricht , The Netherlands.
  • René Monshouwer
    Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Johan Bussink
    Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Gareth Price
    c The University of Manchester, Manchester Academic Health Science Centre, The Christie NHS Foundation Trust , Manchester , UK.
  • Philippe Lambin
    Department of Radiation Oncology (MAASTRO Clinic), Dr. Tanslaan 12, Maastricht, The Netherlands.
  • Andre Dekker
    Department of Radiation Oncology (MAASTRO Clinic), Dr. Tanslaan 12, Maastricht, The Netherlands.

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