DC-AL GAN: Pseudoprogression and true tumor progression of glioblastoma multiform image classification based on DCGAN and AlexNet.

Journal: Medical physics
Published Date:

Abstract

PURPOSE: Pseudoprogression (PsP) occurs in 20-30% of patients with glioblastoma multiforme (GBM) after receiving the standard treatment. PsP exhibits similarities in shape and intensity to the true tumor progression (TTP) of GBM on the follow-up magnetic resonance imaging (MRI). These similarities pose challenges to the differentiation of these types of progression and hence the selection of the appropriate clinical treatment strategy.

Authors

  • Meiyu Li
    College of Electronic Science and Engineering, Jilin University, Changchun, 130012, China.
  • Hailiang Tang
    Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200040, China.
  • Michael D Chan
    Department of Radiation Oncology, Wake Forest Medical School, Winston-Salem, NC 27103, USA.
  • Xiaobo Zhou
    Department of Diagnostic Radiology, Wake Forest Medical School, Winston-Salem, NC 27103, USA. Electronic address: xizhou@wakehealth.edu.
  • Xiaohua Qian
    Department of Diagnostic Radiology, Wake Forest Medical School, Winston-Salem, NC 27103, USA.