A neural network-based joint learning approach for biomedical entity and relation extraction from biomedical literature.

Journal: Journal of biomedical informatics
Published Date:

Abstract

Recently joint modeling methods of entity and relation exhibit more promising results than traditional pipelined methods in general domain. However, they are inappropriate for the biomedical domain due to numerous overlapping relations in biomedical text. To alleviate the problem, we propose a neural network-based joint learning approach for biomedical entity and relation extraction. In this approach, a novel tagging scheme that takes into account overlapping relations is proposed. Then the Att-BiLSTM-CRF model is built to jointly extract the entities and their relations with our extraction rules. Moreover, the contextualized ELMo representations pre-trained on biomedical text are used to further improve the performance. Experimental results on biomedical corpora show that our method can significantly improve the performance of overlapping relation extraction and achieves the state-of-the-art performance.

Authors

  • Ling Luo
    Department of Epidemiology and Medical Statistics School of Public Health, Guangdong Medical University, Dongguan, Guangdong, China.
  • Zhihao Yang
    College of Computer Science and Technology, Dalian University of Technology, Dalian 116024, China.
  • Mingyu Cao
    College of Computer Science and Technology, Dalian University of Technology, Dalian 116024, China.
  • Lei Wang
    Department of Nursing, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Yin Zhang
    Department of Radiation Oncology, Rutgers-Cancer Institute of New Jersey, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, United States.
  • Hongfei Lin