AIMC Topic: Research Design

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Methodological conduct and risk of bias in studies on prenatal birthweight prediction models using machine learning techniques: a systematic review.

BMC pregnancy and childbirth Jul 2, 2025
OBJECTIVE: To assess the methodological quality and the risk of bias, of studies that developed prediction models using Machine Learning (ML) techniques to estimate prenatal birthweight.
Machine Learning Research Design Pregnancy Humans Bias Birth Weight Fetal Weight Female Infant, Newborn Reproducibility of Results
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Mortality risk associated with clinical signs of possible serious bacterial infection (PSBI) in young infants in Africa and Asia: protocol for a secondary pooled analysis.

BMJ open Jun 24, 2025
INTRODUCTION: The WHO's Integrated Management of Childhood Illness (IMCI) in young infants <2 months of age includes the identification and management of signs of possible serious bacterial infection (PSBI). However, equal importance is given to all ...
Humans Research Design Risk Factors Bacterial Infections Female Infant Mortality Infant Infant, Newborn Asia Africa
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Study protocol for the Rainbow Austrian Longitudinal Family (RALF) study: a longitudinal, multi-method, multi-rater investigation of risk and resilience factors in Austrian LGBTQ+ parent families.

BMC psychology May 26, 2025
BACKGROUND: Research on LGBTQ+ parent families is evolving to include a growing range of family systems, identities, methodologies, and topics. However, studies that examine minority-specific risk and resilience factors and their associations with wi...
Austria Family Parents Longitudinal Studies Sexual and Gender Minorities Resilience, Psychological Child Humans Research Design Female Risk Factors Adult Male
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Characterising physical activity patterns in community-dwelling older adults using digital phenotyping: a 2-week observational study protocol.

BMJ open May 24, 2025
INTRODUCTION: Physical activity (PA) is crucial for older adults' well-being and mitigating health risks. Encouraging active lifestyles requires a deeper understanding of the factors influencing PA, which conventional approaches often overlook by ass...
Aged, 80 and over Male Exercise Wearable Electronic Devices Smartphone Observational Studies as Topic Phenotype Female Aged Motivation Self Report Humans Independent Living Heart Rate Research Design Ecological Momentary Assessment
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Using Large Language Models for Advanced and Flexible Labelling of Protocol Deviations in Clinical Development.

Therapeutic innovation & regulatory science May 13, 2025
BACKGROUND: As described in ICH E3 Q&A R1 (International Council for Harmonisation. E3: Structure and content of clinical study reports-questions and answers (R1). 6 July 2012. Available from: https://database.ich.org/sites/default/files/E3_Q%26As_R1...
Large Language Models Humans Research Design Natural Language Processing
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The role of artificial intelligence in the prediction, identification, diagnosis and treatment of perinatal depression and anxiety among women in LMICs: a systematic review protocol.

BMJ open Apr 27, 2025
INTRODUCTION: Perinatal depression and anxiety (PDA) is associated with a high risk of maternal mortality. Existing data shows that 95% of maternal mortality in low- and middle-income countries (LMICs) is due to resource constraints and negligence in...
Systematic Reviews as Topic Humans Developing Countries Artificial Intelligence Research Design Pregnancy Complications Anxiety Pregnancy Depression Female
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Designing Clinical Trials for Patients With Rare Cancers: Connecting the Zebras.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting Apr 14, 2025
The field of rare cancer research is rapidly transforming, marked by significant progress in clinical trials and treatment strategies. Rare cancers, as defined by the National Cancer Institute, occur in fewer than 150 cases per million people each ye...
Rare Diseases Neoplasms Clinical Trials as Topic Humans Research Design Precision Medicine
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Health Care Social Robots in the Age of Generative AI: Protocol for a Scoping Review.

JMIR research protocols Apr 14, 2025
BACKGROUND: Social robots (SR), sensorimotor machines designed to interact with humans, can help to respond to the increasing demands in the health care sector. To ensure the successful use of this technology, acceptance is paramount. Generative arti...
Delivery of Health Care Humans Robotics Artificial Intelligence Scoping Review as Topic Research Design
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Using the counterfactual framework to estimate non-intention-to-treat estimands in randomised controlled trials: A methodological scoping review.

Contemporary clinical trials Apr 11, 2025
BACKGROUND: Randomised controlled trials (RCTs) commonly estimate intention-to-treat (ITT) estimands. However, when nonadherence to assigned treatment occurs, ITT estimands reflect the effect of being offered treatment, rather than adhering to it and...
Humans Research Design Scoping Review as Topic Randomized Controlled Trials as Topic Data Interpretation, Statistical Intention to Treat Analysis
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Role of artificial intelligence-powered conversational agents (chatbots) in musculoskeletal disorders: a scoping review protocol.

BMJ open Mar 24, 2025
INTRODUCTION: Musculoskeletal disorders (MSDs) represent a significant global health burden that leads to substantial disability with socioeconomic impact. With the rise of artificial intelligence (AI), particularly large language model-driven conver...
Research Design Communication Musculoskeletal Diseases Humans Artificial Intelligence
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