Characterization of Central Visual Field Loss in End-stage Glaucoma by Unsupervised Artificial Intelligence.

Journal: JAMA ophthalmology
Published Date:

Abstract

IMPORTANCE: Although the central visual field (VF) in end-stage glaucoma may substantially vary among patients, structure-function studies and quality-of-life assessments are impeded by the lack of appropriate characterization of end-stage VF loss.

Authors

  • Mengyu Wang
    Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts.
  • Jorryt Tichelaar
    Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts.
  • Louis R Pasquale
    Eye and Vision Research Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
  • Lucy Q Shen
    Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.
  • Michael V Boland
    Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Sarah R Wellik
    Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida.
  • Carlos Gustavo De Moraes
    Bernard and Shirlee Brown Glaucoma Research Laboratory, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, New York.
  • Jonathan S Myers
    Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Pradeep Ramulu
    Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • MiYoung Kwon
    Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham.
  • Osamah J Saeedi
    Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore.
  • Hui Wang
    Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
  • Neda Baniasadi
    Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, United States.
  • Dian Li
    Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts.
  • Peter J Bex
    Department of Psychology, Northeastern University, Boston, Massachusetts.
  • Tobias Elze
    Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts; Complex Structures in Biology and Cognition, Max Planck Institute for Mathematics in the Sciences, Leipzig, Germany. Electronic address: tobias-elze@tobias-elze.de.