Deep Learning Automated Detection of Reticular Pseudodrusen from Fundus Autofluorescence Images or Color Fundus Photographs in AREDS2.

Journal: Ophthalmology
Published Date:

Abstract

PURPOSE: To develop deep learning models for detecting reticular pseudodrusen (RPD) using fundus autofluorescence (FAF) images or, alternatively, color fundus photographs (CFP) in the context of age-related macular degeneration (AMD).

Authors

  • Tiarnan D L Keenan
    Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
  • Qingyu Chen
    Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, CT, USA.
  • Yifan Peng
    Department of Population Health Sciences, Weill Cornell Medicine, New York, USA.
  • Amitha Domalpally
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.
  • Elvira Agrón
    National Eye Institute, National Institutes of Health, Bethesda, Maryland.
  • Christopher K Hwang
    Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
  • Alisa T Thavikulwat
    Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
  • Debora H Lee
    Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
  • Daniel Li
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland.
  • Wai T Wong
    National Eye Institute, National Institutes of Health, Bethesda, Maryland.
  • Zhiyong Lu
    National Center for Biotechnology Information, Bethesda, MD 20894 USA.
  • Emily Y Chew
    National Eye Institute, National Institutes of Health, Bethesda, Maryland. Electronic address: echew@nei.nih.gov.