Prediction of mortality in Intensive Care Units: a multivariate feature selection.
Journal:
Journal of biomedical informatics
PMID:
32454242
Abstract
CONTEXT: The critical nature of patients in Intensive Care Units (ICUs) demands intensive monitoring of their vital signs as well as highly qualified professional assistance. The combination of these needs makes ICUs very expensive, which requires investment to be prioritized. Administrative issues emerge, and health institutions face dilemmas such as: "How many beds should an ICU provide to serve the population, at the lowest costs" and "Which is the most critical body information to monitor in an ICU?". Due to financial and ethical implications, these judgments require technical and precise knowledge. Decisions have usually relied on clinical scores, like the APACHE (Acute Physiology And Chronic Health Evaluation) and SOFA (Sequential Organ Failure Assessment) scores, which are imprecise and outdated. The popularization of machine learning techniques has shed some light on the topic as a way to renew score purposes. In 2012, the PhysioNet/Computing in Cardiology launched the Challenge - ICU Patients. This Challenge aimed to stimulate the development of techniques to predict mortality in ICUs. Based on biometric and physiological features collected from patients, the participants predicted the patient's death risk by using their classifiers. Several participants achieved results that were better than the results produced by the SOFA and the APACHE scores; the prediction levels were ≈54%, which is weak.