Machine Learning in Cardiology-Ensuring Clinical Impact Lives Up to the Hype.

Journal: Journal of cardiovascular pharmacology and therapeutics
Published Date:

Abstract

Despite substantial advances in the study, treatment, and prevention of cardiovascular disease, numerous challenges relating to optimally screening, diagnosing, and managing patients remain. Simultaneous improvements in computing power, data storage, and data analytics have led to the development of new techniques to address these challenges. One powerful tool to this end is machine learning (ML), which aims to algorithmically identify and represent structure within data. Machine learning's ability to efficiently analyze large and highly complex data sets make it a desirable investigative approach in modern biomedical research. Despite this potential and enormous public and private sector investment, few prospective studies have demonstrated improved clinical outcomes from this technology. This is particularly true in cardiology, despite its emphasis on objective, data-driven results. This threatens to stifle ML's growth and use in mainstream medicine. We outline the current state of ML in cardiology and outline methods through which impactful and sustainable ML research can occur. Following these steps can ensure ML reaches its potential as a transformative technology in medicine.

Authors

  • Adam J Russak
    Department of Internal Medicine, Mount Sinai Hospital, New York, NY, USA.
  • Farhan Chaudhry
    Department of Emergency Medicine and Integrative Biosciences Center, Wayne State University, Detroit, MI, USA.
  • Jessica K De Freitas
    The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, 770 Lexington Ave, 15th Fl, New York, NY, 10065, USA.
  • Garrett Baron
    Department of Emergency Medicine and Integrative Biosciences Center, Wayne State University, Detroit, MI, USA.
  • Fayzan F Chaudhry
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Solomon Bienstock
    Department of Internal Medicine, Mount Sinai Hospital, New York, NY, USA.
  • Ishan Paranjpe
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Akhil Vaid
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.
  • Mohsin Ali
    Institute for Next Generation Healthcare, Mount Sinai Health System, New York, New York; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Shan Zhao
    Department of Mathematics, University of Alabama, Tuscaloosa, AL 35487-0350, USA.
  • Sulaiman Somani
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.
  • Felix Richter
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Tejeshwar Bawa
    Department of Emergency Medicine and Integrative Biosciences Center, Wayne State University, Detroit, MI, USA.
  • Phillip D Levy
    Department of Emergency Medicine and Integrative Biosciences Center, Wayne State University, Detroit, MI, USA.
  • Riccardo Miotto
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA, and also with the Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.
  • Girish N Nadkarni
    Division of Data-Driven and Digital Medicine (D3M), Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Kipp W Johnson
  • Benjamin S Glicksberg
    The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, 770 Lexington Ave, 15th Fl, New York, NY, 10065, USA.