Machine learning techniques for sequence-based prediction of viral-host interactions between SARS-CoV-2 and human proteins.

Journal: Biomedical journal
PMID: 33036956

Abstract

BACKGROUND: COVID-19 (Coronavirus Disease-19), a disease caused by the SARS-CoV-2 virus, has been declared as a pandemic by the World Health Organization on March 11, 2020. Over 15 million people have already been affected worldwide by COVID-19, resulting in more than 0.6 million deaths. Protein-protein interactions (PPIs) play a key role in the cellular process of SARS-CoV-2 virus infection in the human body. Recently a study has reported some SARS-CoV-2 proteins that interact with several human proteins while many potential interactions remain to be identified.

Authors

  • Lopamudra Dey
    Department of Computer Science & Engineering, Heritage Institute of Technology, Kolkata, India; Department of Information Technology, Techno Main, Saltlake, Kolkata, India; Department of. Computer Science & Engineering, University of Kalyani, Kalyani, India.
  • Sanjay Chakraborty
    Department of Computer Science & Engineering, Heritage Institute of Technology, Kolkata, India; Department of Information Technology, Techno Main, Saltlake, Kolkata, India; Department of. Computer Science & Engineering, University of Kalyani, Kalyani, India.
  • Anirban Mukhopadhyay
    Zuse Institute Berlin, Berlin, Germany.

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