Toward a hemorrhagic trauma severity score: fusing five physiological biomarkers.

Journal: Journal of translational medicine
Published Date:

Abstract

BACKGROUND: To introduce the Hemorrhage Intensive Severity and Survivability (HISS) score, based on the fusion of multi-biomarker data; glucose, lactate, pH, potassium, and oxygen tension, to serve as a patient-specific attribute in hemorrhagic trauma.

Authors

  • Ankita Bhat
    Center for Bioelectronics, Biosensors and Biochips (C3B®), Department of Biomedical Engineering, Texas A&M University, College Station, TX, 77843, USA.
  • Daria Podstawczyk
    Department of Process Engineering and Technology of Polymer and Carbon Materials, Wroclaw University of Science and Technology, Norwida 4/6, 50-373, Wroclaw, Poland.
  • Brandon K Walther
    Center for Bioelectronics, Biosensors and Biochips (C3B®), Department of Biomedical Engineering, Texas A&M University, College Station, TX, 77843, USA.
  • John R Aggas
    Center for Bioelectronics, Biosensors and Biochips (C3B®), Department of Biomedical Engineering, Texas A&M University, College Station, TX, 77843, USA.
  • David Machado-Aranda
    Departments of Emergency Medicine and Biomedical Engineering, Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Kevin R Ward
  • Anthony Guiseppi-Elie
    Center for Bioelectronics, Biosensors and Biochips (C3B®), Department of Biomedical Engineering, Texas A&M University, College Station, TX, 77843, USA. guiseppi@TAMU.edu.